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VayTek offers Advanced Image Processing Systems, including both hardware and software for:

  • Microscopy
  • Industrial Inspection
  • Medical Imaging
  • Quality Control
  • Non-Destructive Testing
  • Deconvolution of Confocal Images
  • 3D Volume Visualization and Measurement

VayTek, Inc.
305 West Lowe Ave.
Fairfield, IA
Tel 641-472-2227
Fax 641-472-8131
Email vaytek@vaytek.com

 

 

 

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3-D oocyte
frog oocyte data, courtesty D. Gard
Processed with VoxBlast, movie.

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VayTek, Inc.
305 West Lowe Ave.
Fairfield, IA
Tel 641-472-2227
Fax 641-472-8131
Email vaytek@vaytek.com

 

 

 

Return to Homepage

 

Application Notes

Bibliography

Cameras

Compare Cameras

Data Acquisition

Deconvolution Algorithms

Distributors

FAQ

Free Demo Software

Homepage

Imaging Mall

Microscopes

MicroTome for Macintosh

MicroTome for Windows

New

Product Guide

Send a File

Services

Stereo Pairs

Site Map

VoxBlast

VoxBlast Movies

 

Return to Homepage

 

Copyright
All information on this World Wide Web site is copyrighted and may be reproduced only with permission from VayTek, Inc.

Customer Comments

"Genetic mosaic analysis reveals that the bulb region of anagen hair follicles contains several active multipotent stem cells. The digital 3-dimensional reconstruction of these follicles with VayTek's VoxBlast allowed us to address largely unanswered questions in the field of mammalian stem biology that have been articulated and pursued by Mintz and coworkers. How many active stem cells participate in the generation of a particular structure? In structures that are supplied by more than one oligo- or multipotent stem cell, is the fraction contribution of each stem cell to the structure fixed, or does the activity of a given stem cell fluctuate over time?"

See the Application Note: Active Stem Cell Participation in the Generation and Maintenance of an Epithelium

Raphael Kopan, Associate Professor
Department of Molecular Biology and Pharmacology
and Department of Medicine (Division of Dermatology)
Washington University,
http://molecool.wustl.edu/Kopan.html

CHO image

"We have used (and continue to use) VoxBlast here in the Confocal Imaging Facility at Monash University for several projects that require volume visualization and analysis. I find it a great programme with easy to implement rendering and visualization features, and users get good results after a reasonably short training session. This is a good package, and I watch with interest as it continues to get better. Moreover, the software development team and tech support is amenable to interaction with users both regarding needed features and assistance with application problems."

-- Dr. Ian S. Harper, Confocal Imaging Facility, Department of Biological Sciences, Monash University, Australia

Image courtesy of Doctors Ian S. Harper, Yuping Yuan and Shaun Jackson (see Journal of Biological Chemistry 274:36241-36251, 1999)

See application note for more information on CHO research; and see VoxBlast movie of ureteric tree of a rat kidney for further examples of work by Dr. Harper and his team.

Zumpano picture
Michael P. Zumpano, Ph.D.

Michael Zumpano has a Ph.D. in Anthropology from SUNY Buffalo. He completed a two year post-doctoral fellowship at The Johns Hopkins School of Medicine in the Department of Cell Biology and Anatomy. Dr. Zumpano currently holds an assistant professor rank and teaches gross anatomy and neuroanatomy at The New York Chiropractic College in Seneca Falls, NY.

macaque skull"I use VoxBlast to create 3D reconstructions from 2D-CT scans of fetal primate skulls and to collect landmark coordinate data from the 3D
reconstructions. From these coordinate data, I determine how the primate skull grows during the fetal period. VoxBlast is a great program, simple to use and excellent graphic rerndering for a PC. I used to work on an SGI with Voxel View."



"I wanted to thank you directly for the continuing help and effort you have afforded me in trying to get my DMRXA set up for deconvolution. If I had it to do all over again, I would have paid closer attention to your original warnings about automated scopes, but I guess I fell in love with the optics on this scope-- and we all know what love can do to logic! In any case, your and Karl's efforts have been fantastic, and I wanted to let you know that they haven't gone unappreciated. If you would like to include my name on a list of people that can provide reference for the quality and service of Vaytek, please do so. Again, thank you!"
William G. Kelly, Ph.D., Assistant Professor of Biology
Biology Department, Emory University
1510 Clifton Rd, Atlanta, GA 30322


"VayTek's VoxBlast is easy to use and has an opacity setting that lets me see inside the data set. Without this feature some structures would not be visible." -- Lance Rodenkirch, Lab Manager, W.M. Keck Neural Imaging Lab, Madison, Wisconsin

See application note for more information and images pertaining to Lance's research.

Lance in lab photo

Dr. Kraig photo

"VayTek has been an excellent resource for our lab. VayTek digital imaging software gives us deconvolution and 3Dimensional reconstruction capabilities. Work in our lab centers on understanding glia, fundamental cells within the brain. VayTek has helped to integrate hardware and software for our demanding research needs. -- Richard Kraig, Ph. D., M.D.; Department of Neurology, University of Chicago.

For more information, see these application notes:
Responses of Neural Tissue to Physiological and Pathological Stimuli, Richard Kraig, Ph.D., M.D.
Deconvolution and 3D Reconstruction of Microglial Cell in Study of Alzheimer's Disease, Richard Kraig, Ph.D., M.D.
Hippocampal Organotypic Culture (HOTC), Deconvolution and 3-D Reconstruction, with an empirically sampled PSF. Richard Kraig, Ph.D., M.D.

"VayTek's deconvolution and 3D reconstruction software has been at the core of our advanced light microscope imaging facility since 1994. The scientists at VayTek understand our research needs, and they have the expertise to put a whole system together." -- Don Phipps, Orange County Water District, Biotechnology Research Department. For more information, see this application note: Digital Deconvolution/3D Image Reconstruction System, Orange County Water District Biotechnology Research Department. -- Don Phipps
microbial biofilm

stable table & microscope
Customer Comments: We used VayTek's Stable Table throughout our 8-day 2000 course in Biological Atomic Force Microscopy at Johns Hopkins. We used it with two different Atomic Force Microscopes: a Digital Instruments Multimode and a Digital Instruments Bioscope. The Stable Table definitely helped reduce vibration noise in both cases. For the Multimode, it helped some, but not as much as we would have liked. It seemed to work much better with the Bioscope. One of our instructors, Dr. Kevin Costa, uses a Stable Table for his work, which is primarily cellular imaging and mechanics with a DI Bioscope. The bearings were too stiff for the Multimode, because it is a fairly light instrument. [Note from VayTek: Bearings may be adjusted for the weight of the instrument.] The Bioscope, however, is mounted on an inverted optical microscope, and the whole setup ends up weighing more than 50 pounds. We ended up adding weight (dumbells, actually) to the Stable Table when using it with the Multimode. We added enough weight so that the table was floating freely. The vibration isolation system we use is quite simple, but seems to provide by far the best results: a 400 pound marble block suspended from an I-beam in the ceiling by bungee cords. In our experience, this system works better than any other vibration isolation system, including active piezoelectric systems. Of course, its not exactly portable. One of the things we liked about the Stable Table was its small size and portability. It was quite easy to move it around from lab to lab and to different instruments, and didn't take up much space. -- Alex Hodges, Johns Hopkins

Wamhoff photo

"Viewing living (not fixed) cells and looking at changes in morphology, organelle distribution, DNA content and physiological responses simultaneously is unprecedented." -- Brain R. Wamhoff, Dept. of Physiology, Dalton Cardiovascular Research Center, Columbia, MO, USA.

See the application note for more images and more information.

"...VoxBlast knocked my socks off. . . .The 3D images tell me things I didn't know before, and confirm things I suspected, but couldn't show to others. . . The end results you get with VoxBlast are fun. It's so much fun, I can sit here for hours doing it." -- David Gard, Ph.D., Biology Department, University of Utah, Salt Lake City, UT. See VoxsBlast-generated movie.


"Your website is the best "informational" site on the subject I have seen to date."
Rosemary Walsh, Manager, The Electron Microscope Facility for the Life Sciences, Penn State University, University Park, PA 16802

M.C., Pioneer Hi-Bred , Johnston, IA says, "We opted for VayTek's system based on. . .

  • Flexibility -VayTek does not force the end user to buy a complete system. Within limits, the choice of the computer, microscope, camera, and ancillary equipment is the researcher's preference."
  • Price - selling well below the other competitors.
  • Speed - Using the zero or nearest-neighbor algorithms, I am able to deconvolve stacks of 12-bit grayscale images in seconds compared to minutes from the competition.
  • Quality Images - I work with plant cells which are notorious for their auto-fluorescence, and VayTek's MicroTome software does an excellent job in cleaning them up.
  • 3D Rendering - for the price, VoxBlast, VayTek's 3D visualization program, has no equal."


Confocal Listserver Questions and Answers, Comparing VoxBlast to Voxel View:
On the basis of cost vs. performance, what Windows or Mac software would fulfill needs for
1) for volume surface rendering and rotation, and
2) for volume rendering combined with the ability to calculate volumes and distances between points on a surface?

"We use both Voxel View from Vital Images, on SGI platforms, and VoxBlast (Vaytek Systems) on PCs. VoxelView is certainly more user friendly and is easier for a beginner to get started with, but VoxBlast is very powerful and in our experience people get to love it once they know it." -- Dr. Guy Cox, University of Sydney , NSW 2006, Australia

Does anyone out there have any experience/comments on the software package for volume rendering VoxBlast for Win95? Thanks for any tips.

"I use it and like it. I also have Voxel-View on the Silicon Graphics. Voxel-view has the slicker interface but VoxBlast is more versatile once you get into it. VoxBlast also reads a much wider range of file formats. Of course PC hardware has its limitations and if you are getting VoxBlast you should be thinking of a very highly specified PC - we use a Pentium 166 with 128MB RAM." -- Dr. Guy Cox, University of Sydney , NSW 2006,Australia


"In addition to the high quality images we were impressed by the flexibility of VayTek's software and its usefulness for many types of applications. After almost two years of comparisons of cameras, computers, and especially, software we think we have made the right choice in terms of a high quality system with the flexibility that we need for multiple users." -- T.T. and S.B., University of Missouri , St. Louis, MO


"VayTek's MicroTome software is absolutely key to my work. The need is to have some method of removing out-of-focus haze whether that is laser scanning confocal or MicroTome, the digital approach. The MicroTome software works great for me! Is is so economical in comparison and the images I get are comparable. But there is no comparison in terms of the cost. There is no way I could do the research I'm doing if this product didn't exist." -- G.G., Infectious Diseases, VA Medical Center, Omaha, NE


"MicroTome does the job where the scanning confocal does not. It has to do with light sensitivity. You can see certain images with VayTek's MicroTome software where you can't see anything at all with scanning confocal." -- S.R., Columbia University, New York, NY

Richard Baird uses VayTek's software, MicroTome, extensively at Washington University, Central Institute for the Deaf, 4560 Clayton Ave, St. Louis MO 63110